T2DAG – Hotelling’s T 2-type Test for detecting differentially Expressed Gene Pathways

T2DAG

:: DESCRIPTION

T2-DAG is an R package of DAG-informed two-sample test for mean difference in the vector of gene expression levels of a pathway. In addition to gene expression data, the method efficiently leverages axiliary pathway information on gene interactions through a linear structural equation model.

::DEVELOPER

Jin Jin

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Windows / Linux
R

:: DOWNLOAD

T2-DAG

:: MORE INFORMATION

Citation:

Jin J, Wang Y.
T2-DAG: a powerful test for differentially expressed gene pathways via graph-informed structural equation modeling.
Bioinformatics. 2021 Nov 10:btab770. doi: 10.1093/bioinformatics/btab770. Epub ahead of print. PMID: 34755844.

PathwaysWeb 2.0 – Gene Pathways API with Directional Interactions, Expanded Gene Ontology, and Versioning

PathwaysWeb 2.0

:: DESCRIPTION

PathwaysWeb provides publicly available information on genes, biological pathways, Gene Ontology terms, gene gene interaction networks with interaction directionality, and links to related PubMed documents.

::DEVELOPER

PathwaysWeb team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

WEb browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

PathwaysWeb: A Gene Pathways API with Directional Interactions, Expanded Gene Ontology, and Versioning.
Melott JM, Weinstein JN, Broom BM.
Bioinformatics. 2015 Sep 23. pii: btv554.