CORNA 1.3 – Testing Gene Lists for Regulation by microRNAs

CORNA 1.3

:: DESCRIPTION

CORNA is a package for R that analyses microarray data and miRNA target prediction data to find statistically over-represented miRNA-target relationships.

::DEVELOPER

CORNA team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • R package

:: DOWNLOAD

 CORNA

:: MORE INFORMATION

Citation

Bioinformatics. 2009 Mar 15;25(6):832-3. doi: 10.1093/bioinformatics/btp059. Epub 2009 Jan 29.
CORNA: testing gene lists for regulation by microRNAs.
Wu X1, Watson M.

GLAD4U 2018 – Gene List Automatically Derived For You

GLAD4U 2018

:: DESCRIPTION

GLAD4U is a new, free web-based gene retrieval and prioritization tool. GLAD4U takes advantage of existing resources of the NCBI to ensure computational efficiency.

::DEVELOPER

the Zhang Lab

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Genomics. 2012;13 Suppl 8:S20. doi: 10.1186/1471-2164-13-S8-S20. Epub 2012 Dec 17.
GLAD4U: deriving and prioritizing gene lists from PubMed literature.
Jourquin J1, Duncan D, Shi Z, Zhang B.

GeneValorization – Gene List significance at-a-glance

GeneValorization

:: DESCRIPTION

GeneValorization is a web-based Java application tool  which aims at making the most of the text-mining effort done downstream to all high throughput technology assays.GeneValorization gives a very clear and handful overview of the bibliography corresponding to one particular gene list.

::DEVELOPER

GeneValorization team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Apr 15;27(8):1187-9. doi: 10.1093/bioinformatics/btr073. Epub 2011 Feb 23.
Gene List significance at-a-glance with GeneValorization.
Brancotte B1, Biton A, Bernard-Pierrot I, Radvanyi F, Reyal F, Cohen-Boulakia S.

WeiSum – Finding Genetic Overlaps among Diseases Based on Ranked Gene Lists

WeiSum

:: DESCRIPTION

WeiSum is an R package which calculates the statistics for the comparison of two ranked gene lists related to two diseases and estimates the number of potentially overlapping genes between the diseases.

::DEVELOPER

Fengzhu Sun

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • R

:: DOWNLOAD

 WeiSum

:: MORE INFORMATION

Citation

Quan Chen, Xianghong Jasmine Zhou, Fengzhu Sun (2015)
Finding Genetic Overlaps Among Diseases Based on Ranked Gene Lists.
In Press. Journal of Computational Biology.

NetVenn – Network Analysis Web platform for Gene Lists

NetVenn

:: DESCRIPTION

NetVenn is a network-based web platform for the comparison and analysis of gene lists by combining Venn diagram and gene set enrichment.

::DEVELOPER

NetVenn team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

NetVenn: an integrated network analysis web platform for gene lists.
Wang Y, Thilmony R, Gu YQ.
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W161-6. doi: 10.1093/nar/gku331.

GeneNomenclatureUtils – Tools for Annotating Genes and Comparing Gene Lists with Community Resources

GeneNomenclatureUtils

:: DESCRIPTION

GeneNomenclatureUtils is a command-line utilities for using MGI, Entrez, HGNC, PubMed, and OMIM files.

::DEVELOPER

Genes to Cognition (G2C)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 GeneNomenclatureUtils

:: MORE INFORMATION

EHR-Phenolyzer v1.0.1 – takes Clinical notes from EHRs and Generate Phenotype terms, then generate ranked Gene List

EHR-Phenolyzer v1.0.1

:: DESCRIPTION

EHR-Phenolyzer is a python pipeline to automatically translate raw clinical notes into meaningfully ranked candidate causal genes. It might greatly shorten the time for disease causal genes identification and discovery.

::DEVELOPER

Wang Genomics Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

EHR-Phenolyzer

:: MORE INFORMATION

Citation

Son JH, Xie G, Yuan C, Ena L, Li Z, Goldstein A, Huang L, Wang L, Shen F, Liu H, Mehl K, Groopman EE, Marasa M, Kiryluk K, Gharavi AG, Chung WK, Hripcsak G, Friedman C, Weng C, Wang K.
Deep Phenotyping on Electronic Health Records Facilitates Genetic Diagnosis by Clinical Exomes.
Am J Hum Genet. 2018 Jul 5;103(1):58-73. doi: 10.1016/j.ajhg.2018.05.010. Epub 2018 Jun 28. PMID: 29961570; PMCID: PMC6035281.

ChEA3 – Gene-list Enrichment Analysis against the manual database

ChEA3

:: DESCRIPTION

ChEA (ChIP-X Enrichment Analysis) database contains manually extracted datasets of transcription-factor/target-gene interactions from over 100 experiments such as ChIP-chip, ChIP-seq, ChIP-PET applied to mammalian cells. We use the database to analyze mRNA expression data where we perform gene-list enrichment analysis as the prior biological knowledge gene-list library. The system is delivered as web-based interactive software. With this software users can input lists of mammalian genes for which the program computes over-representation of transcription factor targets from the ChEA database.

::DEVELOPER

Ma’ayan Laboratory

:: SCREENSHOTS

ChEA

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 ChEA

:: MORE INFORMATION

Citation

ChEA3: transcription factor enrichment analysis by orthogonal omics integration.
Keenan AB, Torre D, Lachmann A, Leong AK, Wojciechowicz ML, Utti V, Jagodnik KM, Kropiwnicki E, Wang Z, Ma’ayan A.
Nucleic Acids Res. 2019 Jul 2;47(W1):W212-W224. doi: 10.1093/nar/gkz446.

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments.
Lachmann A, Xu H, Krishnan J, Berger SI, Mazloom AR, Ma’ayan A.
Bioinformatics. 2010 Oct 1;26(19):2438-44.

Enrichr – HTML5 Gene List Enrichment Analysis Tool

Enrichr

:: DESCRIPTION

Enrichr is an integrative web-based and mobile gene-list enrichment analysis tool that includes over 30 gene-set libraries, an alternative approach to rank enriched terms, and various interactive visualization approaches to display enrichment results using the JavaScript library Data Driven Documents (D3).

::DEVELOPER

Ma’ayan Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2013 Apr 15;14:128. doi: 10.1186/1471-2105-14-128.
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool.
Chen EY, Tan CM, Kou Y, Duan Q, Wang Z, Meirelles GV, Clark NR, Ma’ayan A.
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GeneVenn – Gene list Venn Diagram

GeneVenn

:: DESCRIPTION

 GeneVenn is a web application creating Venn diagrams from two or three gene lists. Each gene in the group list has link to the related information in NCBI’s Entrez Nucleotide database.

::DEVELOPER

the Experimental Bioinformatics Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

GeneVenn – A web application for comparing gene lists using Venn diagrams.
Pirooznia M, Nagarajan V, Deng Y.
Bioinformation. 2007 Apr 10;1(10):420-2.