GEM 1.4.1 – Gene-Environment interaction analysis for Millions of samples

GEM 1.4.1

:: DESCRIPTION

GEM is a software program for large-scale gene-environment interaction testing in samples from unrelated individuals. It enables genome-wide association studies in up to millions of samples while allowing for multiple exposures, control for genotype-covariate interactions, and robust inference.

::DEVELOPER

GEM team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

GEM

:: MORE INFORMATION

Citation

Westerman KE, Pham DT, Hong L, Chen Y, Sevilla-González M, Sung YJ, Sun YV, Morrison AC, Chen H, Manning AK.
GEM: scalable and flexible gene-environment interaction analysis in millions of samples.
Bioinformatics. 2021 Oct 25;37(20):3514-3520. doi: 10.1093/bioinformatics/btab223. PMID: 34695175; PMCID: PMC8545347.

GEM 3.4 – Study Protein-DNA interaction using ChIP-Seq/ChIP-exo data

GEM 3.4

:: DESCRIPTION

GEM (Genome wide Event finding and Motif discovery) is a software tool to study protein-DNA interaction using ChIP-Seq/ChIP-exo data. GEM resolves ChIP data into explanatory motifs and binding events at unsurpassed spatial resolution by linking binding event discovery and motif discovery with positional priors in the context of a generative model of ChIP data and genome sequence.

:: DEVELOPER

the Gifford Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 GEM

:: MORE INFORMATION

Citation:

Yuchun Guo, Georgios Papachristoudis, Robert C Altshuler, Georg K Gerber, Tommi S Jaakkola, David K Gifford & Shaun Mahony,
Discovering homotypic binding events at high spatial resolution.
Bioinformatics. 2010 Dec 15;26(24):3028-34. Epub 2010 Oct 21. PMID: 20966006.