GC – Frequentist Genomic Control Software

GC

:: DESCRIPTION

GC (Genomic Control) implements the genomic control models introduced in Devlin and Roeder (1999) and further expanded in Bacanu et al. (2002). The program runs in two steps. First, it estimates the inflation factor(s) from a set of “null” loci specified by the user. The program then uses these estimates to test for effects at either a single locus (marginal) or two loci (interaction) with relation to a user specified response variable.

::DEVELOPER

The Devlin lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 GC

:: MORE INFORMATION

Citation:

Devlin, B., Bacanu, S., Roeder, K.,
Genomic Control in the Extreme,”
Nature Genetics, 2004, 36(11):1129-1130.

R-GC-test – Testing Genetic Conflicts (GC)

R-GC-test

:: DESCRIPTION

R-GC-test is an R code for testing genetic conflicts (GC) that increase disease risk in human pregnancy with penalized mixture logistic regression.

::DEVELOPER

Yuehua Cui, Ph.D.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux
  • R

:: DOWNLOAD

 R-GC-test

:: MORE INFORMATION

Citation:

Stat Appl Genet Mol Biol. 2009;8:Article 45. doi: 10.2202/1544-6115.1474. Epub 2009 Oct 23.
A regularized regression approach for dissecting genetic conflicts that increase disease risk in pregnancy.
Li S1, Lu Q, Fu W, Romero R, Cui Y.