GGD-Lasso – Graph-regularized dual Lasso for robust eQTL mapping

GGD-Lasso

:: DESCRIPTION

GGD-Lasso (Graph-regularized Dual Lasso) is a robust approach for eQTL mapping.

::DEVELOPER

Wei Cheng

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler / MatLab

:: DOWNLOAD

 GGD-Lasso

:: MORE INFORMATION

Citation

Bioinformatics. 2014 Jun 15;30(12):i139-i148. doi: 10.1093/bioinformatics/btu293.
Graph-regularized dual Lasso for robust eQTL mapping.
Cheng W, Zhang X, Guo Z, Shi Y, Wang W.

EPSILON – eQTL Prioritization using Similarity Measures derived from Local Interaction Networks

EPSILON

:: DESCRIPTION

EPSILON is an extendable framework for eQTL prioritization, which mitigates the effect of highly connected genes and unreliable interactions by constructing a local network before a network-based similarity measure is applied to select the true causal gene.

::DEVELOPER

Lieven P.C. Verbeke lieven.verbeke@intec.ugent.be or jan.fostier@intec.ugent.be

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Matlab/C++

:: DOWNLOAD

  EPSILON

:: MORE INFORMATION

Citation:

Lieven P. C. Verbeke; Lore Cloots; Piet Demeester; Jan Fostier; Kathleen Marchal
EPSILON: an eQTL prioritization framework using similarity measures derived from local networks
Bioinformatics (2013) 29 (10): 1308-1316.

TreeQTL 2.0 – Hierarchical error control for eQTL studies

TreeQTL 2.0

:: DESCRIPTION

TreeQTL implements a hierarchical multiple testing procedure which allows control of appropriate error rates defined relative to a grouping of the eQTL hypotheses.

::DEVELOPER

Christine B. Peterson (cbpeterson@gmail.com)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOSX / Linux
  • R package

:: DOWNLOAD

TreeQTL

:: MORE INFORMATION

Citation

Peterson CB, Bogomolov M, Benjamini Y, Sabatti C.
TreeQTL: hierarchical error control for eQTL findings.
Bioinformatics. 2016 Aug 15;32(16):2556-8. doi: 10.1093/bioinformatics/btw198. Epub 2016 Apr 19. PMID: 27153635; PMCID: PMC4978936.

seeQTL – A Searchable Human eQTL Browser and database

seeQTL

:: DESCRIPTION

seeQTL is a comprehensive and versatile eQTL database, including various eQTL studies and a meta-analysis of HapMap eQTL information. The database presents eQTL association results in a convenient browser, using both segmented local-association plots and genome-wide Manhattan plots.

::DEVELOPER

Department of Biostatistics, Computer Sciences and Genetics, University of North Carolina at Chapel Hill

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web  Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

K. Xia, A.A. Shabalin, S. Huang, V. Madar, Y.H. Zhou, W. Wang, F. Zou, W. Sun, P.F. Sullivan, and F.A. Wright
seeQTL: A searchable database for human eQTLs
Bioinformatics (2012) 28(3): 451-452

eQTLexplorer 6.0 – eQTL Visualization tool

eQTLexplorer 6.0

:: DESCRIPTION

eQTLexplorer is an eqtl visualization tool that allows users to mine and understand data from a repository of genetical genomics experiments.

::DEVELOPER

Michael Mueller, Jon Mangion

:: SCREENSHOTS

::REQUIREMENTS

  • Linux/Windows/MacOsX
  • Java

:: DOWNLOAD

 eQTLexplorer

:: MORE INFORMATION

Citation

Mueller M et al. (2006)
eQTLexplorer: integrated mining of genetical genomics experiments.
Bioinformatics, 22: 509-11