Al-Eigen – Contact Map Overlap by Alignment of Eigenvectors

Al-Eigen

:: DESCRIPTION

Al-Eigen (Alignment of Eigenvectors)  implements a heuristic procedure for computing a solution to the Contact Map Opverlap (CMO) problem. The algorithm uses the standard eigenvalue decomposition of symmetric matrices to obtain a set of principal eigenvectors weighted by the square root of corresponding eigenvalues. The overlap between the two maps is obtained by computing the optimal global alignment between the respective two sets of weighted eigenvectors.

::DEVELOPER

 Bioinformatics group, Department of Computer Science, University of Bologna

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOsX

:: DOWNLOAD

 Al-Eigen

:: MORE INFORMATION

Citation

Bioinformatics. 2010 Sep 15;26(18):2250-8. Epub 2010 Jul 7.
Fast overlapping of protein contact maps by alignment of eigenvectors.
Di Lena P, Fariselli P, Margara L, Vassura M, Casadio R.

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