MLSTA – Machine Learning Integration for Predicting the Effect of Single Amino Acid Substitutions on Protein Stability

MLSTA

:: DESCRIPTION

MLSTA is a machine learning integration for predicting the effect of single amino acid substitutions on protein stability.

::DEVELOPER

Polymer Research Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser
:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

BMC Struct Biol. 2009 Oct 19;9:66. doi: 10.1186/1472-6807-9-66.
Machine learning integration for predicting the effect of single amino acid substitutions on protein stability.
Ozen A1, Gönen M, Alpaydan E, Haliloğlu T.

Fatsim – Simulate the Effect of extracting/not extracting lipids on the outcome of stable Isotope Mixing Models

Fatsim

:: DESCRIPTION

Fatsim is an R-script to simulate the effect of extracting/not extracting lipids on the outcome of stable isotope mixing models

::DEVELOPER

Ehrich, Dorothee

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 Fatsim

:: MORE INFORMATION

Citation:

Tarroux A, Ehrich D, Lecomte N et al. (2010)
Sensitivity of stable isotope mixing models to variation in isotopic ratios: evaluating consequences of lipid extraction.
Methods in Ecology and Evolution, DOI: 10.1111/j.2041-210X.2010.00033.x

SNAP – Predicts Effect of Mutations on Protein Function

SNAP

:: DESCRIPTION

SNAP (screening for non-acceptable polymorphisms) is a method for evaluating effects of single amino acid substitutions on protein function.SNAP identifies over 80% of the non-neutral mutations at 77% accuracy and over 76% of the neutral mutations at 80% accuracy at its default threshold. Each prediction is associated with a reliability index that correlates with accuracy and thereby enables experimentalists to zoom into the most promising predictions.

::DEVELOPER

Yana Bromberg in Rost Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 available upon request.

:: MORE INFORMATION

Citation

SNAP predicts effect of mutations on protein function.
Bromberg Y, Yachdav G, Rost B.
Bioinformatics. 2008 Oct 15;24(20):2397-8. Epub 2008 Aug 30.

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