iDrug-Target
:: DESCRIPTION
By means of the approach of optimizing training datasets, the webserver iDrug-Target was developed for predicting drug-target interaction. It contains four predictors: iDrug-GPCR, iDrug-Chl, iDrug-Ezy, and iDrug-NR, specialized for indentying the interactions of drug compounds with GPCRs (G protein-coupled receptors), ion channels, enzymes, and NR (nuclear receptors), respectively. Rigorous cross-validations on a set of experiment-confirmed datasets have indicated that these new predictors remarkably outperformed their counterparts in the existing prediction methods.
::DEVELOPER
:: SCREENSHOTS
n/a
:: REQUIREMENTS
- Web browser
:: DOWNLOAD
NO
:: MORE INFORMATION
Citation
J Biomol Struct Dyn. 2014 Dec 16:1-27. [Epub ahead of print]
iDrug-Target: Predicting the interactions between drug compounds and target proteins in cellular networking via benchmark dataset optimization approach.
Xiao X1, Min JL, Lin WZ, Liu Z, Cheng X, Chou KC.