antibacTR – Identifying potential Antimicrobial Drug Targets on Gram-negative Bacteria

antibacTR

:: DESCRIPTION

antibacTR (antibacterial Target Ranking) is a computational pipeline designed to aid researchers in the selection of potential drug targets, one of the initial steps in antibacterial-drug discovery.

::DEVELOPER

Xavier Daura

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

BMC Genomics. 2014 Jan 17;15:36. doi: 10.1186/1471-2164-15-36.
antibacTR: dynamic antibacterial-drug-target ranking integrating comparative genomics, structural analysis and experimental annotation.
Panjkovich A, Gibert I, Daura X

DTome – Drug-Target Interactome

DTome

:: DESCRIPTION

DTome provides a computational framework to effectively construct a drug-target networks by integrating the drug-drug interactions, drug-target interactions, drug-gene associations and target/gene-protein interactions.

::DEVELOPER

Bioinformatics and Systems Medicine Laboratory,

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

DTome: a web-based tool for drug-target interactome construction.
Sun J, Wu Y, Xu H, Zhao Z.
BMC Bioinformatics. 2012 Jun 11;13 Suppl 9:S7. doi: 10.1186/1471-2105-13-S9-S7.

DT-Hybrid 0.99.2 – Drug-target Interaction Prediction

DT-Hybrid 0.99.2

:: DESCRIPTION

DT-Hybrid is an R package that implements the homonymous algorithm for the prediction of interactions between small-molecules (i.e. Drug-Target Interactions).

::DEVELOPER

DT-Hybrid team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / WIndows/ MacOsX
  • R

:: DOWNLOAD

 DT-Hybrid

:: MORE INFORMATION

Citation:

Drug-target interaction prediction through domain-tuned network-based inference.
Alaimo S, Pulvirenti A, Giugno R, Ferro A.
Bioinformatics. 2013 Aug 15;29(16):2004-8. doi: 10.1093/bioinformatics/btt307.