HCMV / MRA – Drug / Mutation Resistance Mutations

HCMV / MRA

:: DESCRIPTION

HCMV (human cytomegalovirus) is a new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes.

MRA is a new tool linking drug resistance mutations to resistance phenotypes.

::DEVELOPER

Medical Systems Biology, University of Ulm

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Antiviral Res. 2010 Feb;85(2):318-27. doi: 10.1016/j.antiviral.2009.10.004. Epub 2009 Oct 22.
A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes.
Chevillotte M1, von Einem J, Meier BM, Lin FM, Kestler HA, Mertens T.

CancerDR – Cancer Drug Resistance Database

CancerDR

:: DESCRIPTION

CancerDR is a database of 148 anticancer drugs and their effectiveness against around 1000 cancer cell lines.

::DEVELOPER

CancerDR team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Managing Drug Resistance in Cancer: Role of Cancer Informatics.
Gautam A, Chaudhary K, Kumar R, Gupta S, Singh H, Raghava GP.
Methods Mol Biol. 2016;1395:299-312. doi: 10.1007/978-1-4939-3347-1_17.

vPhyloMM 20090731 – Reconstructs Mutational Pathways of Drug Resistance

vPhyloMM 20090731

:: DESCRIPTION

The purpose of vPhyloMM is to generate a transition model showing the mutational pathways of drug resistance for viruses under drug pressure.

::DEVELOPER

Bioinformatics Research Group (BioRG)

:: SCREENSHOTS

vPhyloMM

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Perl
  • Active Perl 

:: DOWNLOAD

 vPhyloMM

:: MORE INFORMATION

Citation:

Buendia, P., Cadwallader, B. and DeGruttola, V. (2009)
A phylogenetic and Markov model approach for the reconstruction of mutational pathways of drug resistance.
Bioinformatics. 2009 Oct 1;25(19):2522-9. doi: 10.1093/bioinformatics/btp466.

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