srnaloop – Search long DNA/RNA Strings for small RNA Hairpin Loops

srnaloop

:: DESCRIPTION

srnaloop searchs long DNA/RNA strings for small RNA hairpin loops that may be candidates for small RNA regulatory sequences.

::DEVELOPER

George M. Church Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux
  • C Compiler

:: DOWNLOAD

 srnaloop

:: MORE INFORMATION

Citation

Mol Cell. 2003 May;11(5):1253-63.
Computational and experimental identification of C. elegans microRNAs.
Grad Y1, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J.

DNAFSMiner – DNA Functional Site Miner

DNAFSMiner

:: DESCRIPTION

DNAFSMiner is a web-based software toolbox that aims to predict these functional sites in DNA sequences.Currently, there are two software tools. One is called TIS Miner which can be used to predict translation initiation site (TIS) in vertebrate mRNA, cDNA, or DNA sequences. The other is called Poly(A) Signal Miner which can be used to predict polyadenylation (poly(A)) signal in human DNA sequences.

::DEVELOPER

DNAFSMiner team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Bioinformatics. 2005 Mar 1;21(5):671-3. Epub 2004 Jul 29.
DNAFSMiner: a web-based software toolbox to recognize two types of functional sites in DNA sequences.
Liu H1, Han H, Li J, Wong L.

iMolview 1.9.5 – iPhone, iPad and Android App for Browsing Protein, DNA & Drug Molecules in 3D

iMolview 1.9.5

:: DESCRIPTION

iMolview is an app for the iPhone , iPad and Android that lets you browse protein, DNA, and drug molecules in 3D. The app has a direct link to the Protein Data Bank (PDB) and DrugBank and has a fast and easy to use interface. Touching the molecules via the screen allows you to interact immediately with the 3D structures in a unique way. You can zoom in and out, rotate, spin, pan, and clip the 3D molecules with your finger tips in ways that are impossible using a traditional mouse and desktop computer.

::DEVELOPER

Molsoft LLC.

:: SCREENSHOTS

:: REQUIREMENTS

  • IPhone / IPad / Android

:: DOWNLOAD

iMolview

:: MORE INFORMATION

BLAT 36 – Rapid mRNA/DNA & Cross-species Protein Alignments

BLAT 36

:: DESCRIPTION

BLAT (BLAST -like alignment tool) is a bioinformatics software a tool which performs rapid mRNA/DNA and cross-species protein alignments. BLAT is more accurate and 500 times faster than popular existing tools for mRNA/DNA alignments and 50 times faster for protein alignments at sensitivity settings typically used when comparing vertebrate sequences.

BLAT Online Version

::DEVELOPER

Jim Kent

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX

:: DOWNLOAD

 BLAT ; Source Code

:: MORE INFORMATION

Citation

Kent, W.J. 2002.
BLAT — The BLAST-Like Alignment Tool.
Genome Research 4: 656-664

PhyloGibbs-MP 2.0 – Motif Finder in Cis-regulatory Sequences of DNA

PhyloGibbs-MP 2.0

:: DESCRIPTION

PhyloGibbs-MP is a motif finder to find binding sites for transcription factors in cis-regulatory sequences of DNA.

::DEVELOPER

RAHUL SIDDHARTHAN

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows

:: DOWNLOAD

 PhyloGibbs-MP

:: MORE INFORMATION

Citation:

Rahul Siddharthan,
PhyloGibbs-MP: Module Prediction and Discriminative Motif-Finding by Gibbs Sampling“,
PLoS Comput Biol 4(8): e1000156 (2008)

LSPR – Detect Periodic Expression Profiles in DNA Microarray Time-series data

LSPR

:: DESCRIPTION

LSPR is a Matlab package used to detect periodic expression profiles in DNA microarray time-series data.

::DEVELOPER

LSPR team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • MatLab

:: DOWNLOAD

  LSPR

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Apr 1;27(7):1023-5. doi: 10.1093/bioinformatics/btr041. Epub 2011 Feb 3.
LSPR: an integrated periodicity detection algorithm for unevenly sampled temporal microarray data.
Yang R1, Zhang C, Su Z.

GATK 4.2.2.0 – Analysis Tools for Next-generation DNA Sequencers

GATK 4.2.2.0

:: DESCRIPTION

GATK (The Genome Analysis Toolkit) is a structured programming framework designed to enable the rapid development of efficient and robust analysis tools for next-generation DNA sequencers. The GATK solves the data management challenge by separating data access patterns from analysis algorithms, using the functional programming philosophy of Map/Reduce. Since the GATK’s traversal engine encapsulates the complexity of efficiently accessing the next-generation sequencing data, researchers and developers are free to focus on their specific analysis algorithms. This not only vastly improves the productivity of developers, who can quickly write new analyses, but also results in tools that are efficient and robust, and can benefit from improvements to a common data management engine.

::DEVELOPER

The Broad Institute, Cambridge, MA

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

GATK

:: MORE INFORMATION

Citation

Depristo MA, Banks E, Poplin R, Garimella KV, Maguire JR, Hartl C, Philippakis AA, Del Angel G, Rivas MA, Hanna M, McKenna A, Fennell TJ, Kernytsky AM, Sivachenko AY, Cibulskis K, Gabriel SB, Altshuler D, Daly MJ.
A framework for variation discovery and genotyping using next-generation DNA sequencing data
Nature Genetics 43, 491–498 (2011) doi:10.1038/ng.806

ArtWonk v4.4.1740 – DNA to MIDI Converter

ArtWonk v4.4.1740

:: DESCRIPTION

ArtWonk produces music, visuals and wordplay based on generative algorithms you interactively create by connecting modules (graphical objects representing functions and processes) in real time, adjusting the parameters as you go, in a drag & drop environment especially designed to be fast to learn, fast to use.

Source material can be anything at all: Fractals, DNA, EEGs, EKGs, stock quotes, you name it. Built in data extraction reads data from virtually any source, and an extensive DNA editor opens mountains of public domain genetic sequences to explore.

Genetic Music From DNA and Protein

::DEVELOPER

John Dunn and Algorithmic Arts

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

ArtWonk

:: MORE INFORMATION

Citation:

Peter Hamlin
ALGORITHMIC ARTSARTWONK 1.2 (WIN)
2004 issue of Electronic Musician Magazine.

do_x3dna 2018 – Analyze Fluctuations in DNA or RNA Structures in Molecular Dynamics Trajectories

do_x3dna 2018

:: DESCRIPTION

The do_x3dna package has been developed to analyze the structural fluctuations of DNA or RNA during molecular dynamics simulations.

::DEVELOPER

Rajendra Kumar

:: SCREENSHOTS

N/a

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OsX
  • 3DNA

:: DOWNLOAD

 do_x3dna

:: MORE INFORMATION

Citation

do_x3dna: A tool to analyze structural fluctuations of dsDNA or dsRNA from molecular dynamics simulations.
Kumar R, Grubmüller H.
Bioinformatics. 2015 Apr 2. pii: btv190.

StatAlign 3.4 – Bayesian Analysis of Protein, DNA and RNA Sequences

StatAlign 3.4

:: DESCRIPTION

StatAlign is an extendable software package for Bayesian analysis of Protein, DNA and RNA sequences. Multiple alignments, phylogenetic trees and evolutionary parameters are co-estimated in a Markov Chain Monte Carlo framework, allowing for reliable measurement of the accuracy of the results.

::DEVELOPER

StatAlign team

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux/Windows/MacOsx
  • Java

 StatAlign

:: MORE INFORMATION

Citation

Aádám Novák, István Miklós, Rune Lyngsø and Jotun Hein
StatAlign: an extendable software package for joint Bayesian estimation of alignments and evolutionary trees
Bioinformatics (2008) 24 (20): 2403-2404.

Arunapuram P, Edvardsson I, Golden M, Anderson JW, Novák A, Sükösd Z, Hein J (2013)
StatAlign 2.0: Combining statistical alignment with RNA secondary structure prediction. 
Bioinformatics,2013 Mar 1;29(5):654-5. doi:10.1093/bioinformatics/btt025.