DisLocate – Find Disulfide bonds in Eukaryotes with predicted subcellular Localization

DisLocate

:: DESCRIPTION

 DisLocate is a a two-step method based on machine learning models for predicting both the bonding state and the connectivity patterns of cysteine residues in a protein chain.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No. Only Web Service

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Aug 15;27(16):2224-30. Epub 2011 Jun 29.
Improving the prediction of disulfide bonds in Eukaryotes with machine learning methods and protein subcellular localization.
Savojardo C, Fariselli P, Alhamdoosh M, Martelli PL, Pierleoni A, Casadio R.

DIpro 2.0 – Protein Disulfide Bond Prediction

DIpro 2.0

:: DESCRIPTION

DIpro is a cysteine disulfide bond predictor based on 2D recurrent neural network, support vector machine, graph matching and regression algorithms. It can predict if the sequence has disulfide bonds or not, estimate the number of disulfide bonds, and predict the bonding state of each cysteine and the bonded pairs. It yields the best accuracy on the benchmark dataset Sp39. It can handle any number of disulfide bonds where most of methods available so far only can handle less than 6 disulfide bonds.

::DEVELOPER

Institute for Genomics and Bioinformatics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 DIpro

:: MORE INFORMATION

Citation:

J. Cheng, H. Saigo, & P. Baldi.
Large-Scale Prediction of Disulphide Bridges Using Kernel Methods, Two-Dimensional Recursive Neural Networks, and Weighted Graph Matching.
Proteins, vol. 62, no. 3, pp. 617-629, (2006)

DiANNA 1.1 – Cysteine state and Disulfide Bond partner prediction

DiANNA 1.1

:: DESCRIPTION

DiANNA (DiAminoacid Neural Network Application) is a software to predict both cysteine oxidation state and which half-cystines partner with which other half-cystines in disulfide bonds.

::DEVELOPER

Clote Lab 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Mac OsX / Windows
  • WebServer
  • Python

:: DOWNLOAD

 DiANNA

:: MORE INFORMATION

Citation:

F. Ferre, P. Clote,
DiANNA 1.1: An extension of the DiANNA web server for ternary cysteine classification,
Nucleic Acids Res. 34(Web Server issue):W182-5 (2006).