HyDA 1.3.1 / Squeezambler 2.0.3 – Hybrid De Novo Assembler

HyDA 1.3.1 / Squeezambler 2.0.3

:: DESCRIPTION

HyDA is a multipurpose assembler, particularly tested for single cell and normal multicell genome co-assembly

Squeezambler is a divide-and-conquer algorithm for economical sequencing and assembly of all distinct genomes in a bacterial sample. The key idea here is exploiting sparsity, which is the small number of distinct genomes (~1000) in comparison to the huge number of cells (~100 trillion).

::DEVELOPER

Algorithmic Biology Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 HyDA / Squeezamler

:: MORE INFORMATION

Citation:

Narjes S. Movahedi, Elmirasadat Forouzmand, Hamidreza Chitsaz,
De Novo Co-assembly of Bacterial Genomes from Multiple Single Cells,
IEEE International Conference on Bioinformatics and Biomedicine (BIBM), pp 561-565, 2012

Bioinformatics. 2013 Aug 13. [Epub ahead of print]
Distilled single-cell genome sequencing and de novo assembly for sparse microbial communities.
Taghavi Z, Movahedi NS, Draghici S, Chitsaz H.

EPGA2 – De Novo Assembler

EPGA2

:: DESCRIPTION

EPGA is an algorithm which extracts paths from De Bruijn graph for genome assembly.

EPGA2 updates some modules in EPGA which can improve memory efficiency in genome asssembly.

::DEVELOPER

CSU-Bioinformatics Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • C++ Compiler

:: DOWNLOAD

 EPGA ,EPGA2

:: MORE INFORMATION

Citation

EPGA2: memory-efficient de novo assembler.
Luo J, Wang J, Li W, Zhang Z, Wu FX, Li M, Pan Y.
Bioinformatics. 2015 Aug 26. pii: btv487

EPGA: de novo assembly using the distributions of reads and insert size.
Luo J, Wang J, Zhang Z, Wu FX, Li M, Pan Y.
Bioinformatics. 2014 Nov 17. pii: btu762

Fermi 1.1 – WGS de novo Assembler based on the FMD-index for large Genomes

Fermi 1.1

:: DESCRIPTION

Fermi is a de novo assembler for Illumina reads from whole-genome short-gun sequencing. It also provides tools for error correction, sequence-to-read alignment and comparison between read sets. It uses the FMD-index, a novel compressed data structure, as the key data representation.

::DEVELOPER

Heng Li

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

 Fermi

:: MORE INFORMATION

Citation:

Bioinformatics. 2012 Jul 15;28(14):1838-44. doi: 10.1093/bioinformatics/bts280. Epub 2012 May 7.
Exploring single-sample SNP and INDEL calling with whole-genome de novo assembly.
Li H.