RefineTree – Gene Tree Correction software

RefineTree

:: DESCRIPTION

RefineTree is a gene tree correction software, based on resolving a multifurcated gene tree in a way minimizing the reconciliation distance with a given species tree.

::DEVELOPER

NADIA EL-MABROUK

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Genome evolution-aware gene trees
E. Noutahi, M. Semeria, M. Lafond, J. Seguin, B. Boussau, L. Gueguen, N. El-Mabrouk and Eric Taniier,
submitted to PloS.Comp.Biol, 2015.

RNASeqBias 1.0 – Bias Detection and Correction in RNA-Sequencing Data

RNASeqBias 1.0

:: DESCRIPTION

RNASeqBias contains functions and sample data for detecting and correcting for biases in gene expression levels from RNA-Seq experiments. Considered bias factors are gene length, GC content and dinucleotide frequencies. Principal component analysis on GC content and dinucleotide frequencies are first performed, and the resulting principal components and gene length were used as covariates to fit a generalized additive model with smoothing spline on gene expression levels as response. The package also have codes to generate bias plots before and after bias correction, and to compare with other quantitative platforms.

::DEVELOPER

Zhao Hongyu’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 RNASeqBias

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2011 Jul 19;12:290. doi: 10.1186/1471-2105-12-290.
Bias detection and correction in RNA-Sequencing data.
Zheng W1, Chung LM, Zhao H.

CopyNumber450kCancer 1.0.4 – Baseline Correction for Copy Number Data from Cancer Samples

CopyNumber450kCancer 1.0.4

:: DESCRIPTION

CopyNumber450kCancer takes the output of CopyNumber450k and ChAMP packages and correct the baseline in each sample for accurate copy number calling, specially in cancer samples. CopyNumber450kCancer can read the segment output file from CopyNumber450k package directly without any need for modification. Output files from ChAMP need to be in one file not in seperated files.

::DEVELOPER

Molecular Medicine research group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows
  • R

:: DOWNLOAD

 CopyNumber450kCancer

:: MORE INFORMATION

Citation

CopyNumber450kCancer: Baseline Correction for Accurate Copy Number Calling from the 450k Methylation Array.
Marzouka NA, Nordlund J, Bäcklin CL, Lönnerholm G, Syvänen AC, Almlöf JC.
Bioinformatics. 2015 Nov 9. pii: btv652

LMM-Lasso – Lasso Multi-Marker Mixed Model for Association Mapping with Population Structure Correction

LMM-Lasso

:: DESCRIPTION

LMM-Lasso is a linear mixed models that allows for both multi-locus mapping and correction for confounding effects.

::DEVELOPER

Machine Learning and Computational Biology Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • Python

:: DOWNLOAD

 LMM-Lasso

:: MORE INFORMATION

Citation

Bioinformatics. 2013 Jan 15;29(2):206-14. doi: 10.1093/bioinformatics/bts669.
A Lasso multi-marker mixed model for association mapping with population structure correction.
Rakitsch B, Lippert C, Stegle O, Borgwardt K.

NIACS – Network Interference Analysis and Correction Software

NIACS

:: DESCRIPTION

NIACS implements a method for deffining causal networks corrected for the problem of interference between dynamically similar regulators within the context of a sparse linear auto-regression model.

::DEVELOPER

The Warwick Systems Biology Centre (WSB)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / WIndows / MacOsX
  • R

:: DOWNLOAD

 NIACS

:: MORE INFORMATION

Citation

Correcting for link loss in causal network inference caused by regulator interference.
Wang Y, Penfold CA, Hodgson DA, Gifford ML, Burroughs NJ.
Bioinformatics. 2014 Jun 19. pii: btu388.

ACE 1.01 – Accurate Correction of Errors using K-mer tries

ACE 1.01

:: DESCRIPTION

ACE corrects substitution errors in an Illumina archive using a k-mer trie.

::DEVELOPER

ACE team

:: SCREENSHOTS

N/a

:: REQUIREMENTS

  • Linux  /MacOsX
  • C++

:: DOWNLOAD

  ACE

:: MORE INFORMATION

Citation

ACE: Accurate Correction of Errors using K-mer tries.
Sheikhizadeh S, de Ridder D.
Bioinformatics. 2015 May 28. pii: btv332.

CorQ 20130619 – Quality Score based Identification and Correction of Pyrosequencing Errors

CorQ 20130619

:: DESCRIPTION

CorQ (Correction through Quality) is a new algorithm which utilizes the inherent base quality in a sequence-specific context to correct for homopolymer and non-homopolymer insertion and deletion (indel) errors.

::DEVELOPER

Mullins Molecular Retrovirology Lab, University of Washington.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Perl

:: DOWNLOAD

 CorQ

:: MORE INFORMATION

Citation

PLoS One. 2013 Sep 5;8(9):e73015. doi: 10.1371/journal.pone.0073015. eCollection 2013.
Quality score based identification and correction of pyrosequencing errors.
Iyer S1, Bouzek H, Deng W, Larsen B, Casey E, Mullins JI.

RACER 1.0.1 – Rapid and Accurate Correction of Errors in Reads

RACER 1.0.1

:: DESCRIPTION

RACER is a C++/OpenMP program that corrects sequencing errors in high-throughput DNA sequencing data, especially designed for the Illumina platform.

::DEVELOPER

LUCIAN ILIE

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RACER

:: MORE INFORMATION

Citation

Bioinformatics. 2013 Oct 1;29(19):2490-3. doi: 10.1093/bioinformatics/btt407. Epub 2013 Jul 12.
RACER: Rapid and accurate correction of errors in reads.
Ilie L1, Molnar M.

HiTEC 20110131 – Accurate Error Correction in High-throughput Sequencing data

HiTEC 20110131

:: DESCRIPTION

HiTEC (High Throughput Error Correction) , an algorithm that provides a highly accurate, robust and fully automated method to correct reads produced by high-throughput sequencing methods. The approach provides significantly higher accuracy than previous methods. It is time and space efficient and works very well for all read lengths, genome sizes and coverage levels.

::DEVELOPER

LUCIAN ILIE

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 HiTEC

:: MORE INFORMATION

Citation

L. Ilie, F. Fazayeli, S. Ilie,
HiTEC: accurate error correction in high-throughput sequencing data,
Bioinformatics 27(3) (2011) 295 — 302.

LoRDEC 0.9 – A Hybrid Error Correction program for long, PacBio Reads

LoRDEC 0.9

:: DESCRIPTION

LoRDEC is a program to correct sequencing errors in long reads from 3rd generation sequencing with high error rate, and is especially intended for PacBio reads.

::DEVELOPER

The Computational Biology Institute (IBC)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • GATB library

:: DOWNLOAD

 LoRDEC

:: MORE INFORMATION

Citation:

Bioinformatics. 2014 Aug 26. pii: btu538.
LoRDEC: accurate and efficient long read error correction.
Salmela L, Rivals E.