DDN – Identify Condition-specific Topological Changes in Biological Networks

DDN

:: DESCRIPTION

DDN (Differential Dependence Networks) is a software of analysis to detect statistically significant topological changes in the transcriptional networks between two biological conditions. We propose a local dependency model to represent the local structures of a network by a set of conditional probabilities.

::DEVELOPER

Computational Bioinformatics & Bio-imaging Laboratory (CBIL)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

  DDN

:: MORE INFORMATION

Citation:

Bioinformatics. 2011 Apr 1;27(7):1036-8. doi: 10.1093/bioinformatics/btr052. Epub 2011 Feb 3.
DDN: a caBIG® analytical tool for differential network analysis.
Zhang B1, Tian Y, Jin L, Li H, Shih IeM, Madhavan S, Clarke R, Hoffman EP, Xuan J, Hilakivi-Clarke L, Wang Y.

Differential dependency network analysis to identify condition-specific topological changes in biological networks.
Zhang B, Li H, Riggins RB, Zhan M, Xuan J, Zhang Z, Hoffman EP, Clarke R, Wang Y.
Bioinformatics. 2009 Feb 15;25(4):526-32. Epub 2008 Dec 26.