Stubb 2.1 – Finding Cis-regulatory Modules

Stubb 2.1

:: DESCRIPTION

Stubb uses a probabilistic model and a maximum likelihood approach to efficiently detect cis-regulatory modules over genomic scales.

::DEVELOPER

The Sinha Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C++ Compiler
  • Lagan

:: DOWNLOAD

  Stubb

:: MORE INFORMATION

Citation:

Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W555-9.
Stubb: a program for discovery and analysis of cis-regulatory modules.
Sinha S, Liang Y, Siggia E.

JRIM – Joint reconstruct cis-regulatory interaction networks of multiple cell populations

JRIM

:: DESCRIPTION

JRIM is a package for Jointly Reconstructing cis-regulatory Interaction Maps of multiple cell populations using single-cell chromatin accessibility data and identifying shared and common interaction patterns. It uses an aggregation process to deal with the sparsity of single-cell data, exploits similarity between cell types via a group lasso penalty, and generates comparable networks. JRIM could be used to characterize difference between cell types or identify dynamic changes during cell development.

::DEVELOPER

Shihua Zhang’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux
  • R

:: DOWNLOAD

JRIM

:: MORE INFORMATION

Citation

Dong K, Zhang S.
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data.
Brief Bioinform. 2021 May 20;22(3):bbaa120. doi: 10.1093/bib/bbaa120. PMID: 32578841; PMCID: PMC8138825.

Cis-regPred – Cis-regulatory Element Predictor

Cis-regPred

:: DESCRIPTION

Cis-regPred predicts intrinsically disordered protein regions that may regulate protein function by mediating interactions in cis.

::DEVELOPER

Gsponer Lab

:: SCREENSHOTS

N/a

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

NO

:: MORE INFORMATION

Citation

Yeon JH, Heinkel F, Sung M, Na D, Gsponer J.
Systems-wide Identification of cis-Regulatory Elements in Proteins.
Cell Syst. 2016 Feb 24;2(2):89-100. doi: 10.1016/j.cels.2016.02.004. Epub 2016 Feb 24. PMID: 27135163.

cis-Browser 1.0 – Genome Browser for Cis-regulatory Information

cis-Browser 1.0

:: DESCRIPTION

cis-Browser (cis-Regulatory Browser) is genome browser for cis-regulatory information inferring logic functions of genomic cis-regulatory code and the principles of information processing of genomic regulation

::DEVELOPER

The Istrail Laboratory of Brown University

:: SCREENSHOTS

cis-Browser

:: REQUIREMENTS

  • Linux/ Windows/ MacOsX
  • Java

:: DOWNLOAD

 cis-Browser

:: MORE INFORMATION

Citation

Methods Mol Biol. 2010;674:369-99. doi: 10.1007/978-1-60761-854-6_22.
Practical computational methods for regulatory genomics: a cisGRN-Lexicon and cisGRN-browser for gene regulatory networks.
Istrail S, Tarpine R, Schutter K, Aguiar D.