BroadPeak – Broad Peak calling algorithm for Diffuse ChIP-seq Datasets

BroadPeak

:: DESCRIPTION

BroadPeak is an algorithm for the identification of broad peaks from diffuse ChIP-seq datasets.

::DEVELOPER

Jordan Lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux
  • R Program

:: DOWNLOAD

 BroadPeak 

:: MORE INFORMATION

Citation

Bioinformatics. 2013 Feb 15;29(4):492-3. doi: 10.1093/bioinformatics/bts722. Epub 2013 Jan 7.
BroadPeak: a novel algorithm for identifying broad peaks in diffuse ChIP-seq datasets.
Wang J, Lunyak VV, Jordan IK.

MOSAICS 1.0.0 – Analysis of ChIP-seq data

MOSAICS 1.0.0

:: DESCRIPTION

MOSAICS is an R package for the analysis of one-sample or two-sample ChIP-seq data.

::DEVELOPER

Pei Fen Kuan

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 MOSAICS

:: MORE INFORMATION

Citation

Kuan, P., Chung, D., Pan, G., Thomson, J., Stewart, R., and Keles, S. (2011).
A Statistical Framework for the Analysis of ChIP-Seq Data.
Journal of the American Statistical Association

NucHunter – Inferring Nucleosome Positions from ChIP-seq Experiments

NucHunter

:: DESCRIPTION

NucHunter is an algorithm that uses the data from ChIP-seq experiments directed against many histone modifications to infer positioned nucleosomes.

::DEVELOPER

NucHunter team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ WIndows/MacOsX
  • Java

:: DOWNLOAD

 NucHunter

:: MORE INFORMATION

Citation

Bioinformatics. 2013 Oct 15;29(20):2547-54. doi: 10.1093/bioinformatics/btt449. Epub 2013 Aug 26.
Inferring nucleosome positions with their histone mark annotation from ChIP data.
Mammana A1, Vingron M, Chung HR.

cnvCSEM – CNV-guided Multi-read Allocation for ChIP-seq

cnvCSEM

:: DESCRIPTION

cnvCSEM  (CNV: -guided C: hIP-S: eq by E: xpectation-M: aximization algorithm), is a flexible framework that incorporates CNV in multi-read allocation.

::DEVELOPER

Qi Zhang (qizhang at stat dot wisc dot edu)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows / MacOsX
  • C++ Compiler
  • Perl
  • Bowtie
:: DOWNLOAD

 cnvCSEM

:: MORE INFORMATION

Citation

CNV-guided Multi-read Allocation for ChIP-seq.
Zhang Q, Keleş S.
Bioinformatics. 2014 Jun 24. pii: btu402.

Sole-Search v2 – Peak Detection and Functional Annotation using ChIP-seq data

Sole-Search v2

:: DESCRIPTION

Sole-Search is an integrated peak-calling and analysis softwar which is available through a user-friendly interface and (i) converts raw data into a format for visualization on a genome browser, (ii) outputs ranked peak locations using a statistically based method that overcomes the significant problem of false positives, (iii) identifies the gene nearest to each peak, (iv) classifies the location of each peak relative to gene structure, (v) provides information such as the number of binding sites per chromosome and per gene and (vi) allows the user to determine overlap between two different experiments.

::DEVELOPER

Korf Lab at the University of California, Davis.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows/ MacOsX
  • Perl

:: DOWNLOAD

 Sole-Search

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2010 Jan;38(3):e13. doi: 10.1093/nar/gkp1012. Epub 2009 Nov 11.
Sole-Search: an integrated analysis program for peak detection and functional annotation using ChIP-seq data.
Blahnik KR, Dou L, O’Geen H, McPhillips T, Xu X, Cao AR, Iyengar S, Nicolet CM, Lud?scher B, Korf I, Farnham PJ.

CHANCE 2.0 b / CHANCE-HT 20140522 – ChIP-seq Data Pre-processing software

CHANCE 2.0 b / CHANCE-HT 20140522

:: DESCRIPTION

CHANCE (ChIP-seq Analytics and Confidence Estimation) is a software for assessing the quality of ChIP-seq experiments and providing feedback for the optimization of ChIP and library generation protocols.

CHANCE-HT is a ChIP-seq pre-processing software that filters samples with weak IP-strength, identifies heavily biased control experiments and under sequenced samples, detects batch effects, and normalizes large ensembles of ChIP-seq datasets.CHANCE-HT uses a parallel processing approach to normalize and filter large collections of ChIP-seq datasets in tandem.

::DEVELOPER

Diaz Lab , Jun S. Song’s Research Group

:: SCREENSHOTS

CHANCE

:: REQUIREMENTS

  • Windows /Linux/ MacOsX

:: DOWNLOAD

 CHANCE

:: MORE INFORMATION

Citation

A. Diaz, A. Nellore, J.S. Song.
CHANCE: a comprehensive software for quality control and validation of ChIP-seq data,
Genome Biology 13:R98, (2012).

CSDeconv 1.03 – Determine Locations of Transcription Factor Binding from ChIP-seq data

CSDeconv 1.03

:: DESCRIPTION

CSDeconv maps transcription factor binding sites from ChIP-seq data to high resolution using a blind deconvolution approach

::DEVELOPER

Desmond Lun

:: SCREENSHOTS

N/a

::REQUIREMENTS

  • Linux / Windows/ MacOsX
  • MatLab

:: DOWNLOAD

 CSDeconv

:: MORE INFORMATION

Citation

D. S. Lun, A. Sherrid, B. Weiner, D. R. Sherman, and J. E. Galagan.
A blind deconvolution approach to high-resolution mapping of transcription factor binding sites from ChIP-Seq data.
Genome Biol., 10(12):R142, December 2009.

ODIN 0.4.1 – Detecting Differential Peaks in ChIP-seq Signals

ODIN 0.4.1

:: DESCRIPTION

ODIN is a HMM-based approach to detect and analyse differential peaks in pairs of ChIP-seq data. It is the first differential peak caller that performs genomic signal processing, peak calling and p-value calculation in an integrated framework.

::DEVELOPER

IZKF Computational Biology and Bioinformatics Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

 ODIN

:: MORE INFORMATION

Citation:

Detecting differential peaks in ChIP-seq signals with ODIN.
Allhoff M, Seré K, Chauvistré H, Lin Q, Zenke M, Costa IG.
Bioinformatics. 2014 Nov 3. pii: btu722.

ReMap 2020 – ChIP-seq analysis of Regulatory Elements

ReMap 2020

:: DESCRIPTION

ReMap is an integrative analysis of transcription factor ChIP-seq experiments

::DEVELOPER

The TAGC Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

Cheneby J., Menetrier Z., Mestdagh M., Rosnet T., Douida A., Rhalloussi W., Bergon A., Lopez F., Ballester B.
ReMap 2020: A database of regulatory regions from an integrative analysis of Human and Arabidopsis DNA-binding sequencing experiments.
Nucleic Acids Research (2020) gkz945 https://doi.org/10.1093/nar/gkz945.

Integrative analysis of public ChIP-seq experiments reveals a complex multi-cell regulatory landscape.
Griffon A, Barbier Q, Dalino J, van Helden J, Spicuglia S, Ballester B.
Nucleic Acids Res. 2015 Feb 27;43(4):e27. doi: 10.1093/nar/gku1280.

MSPC 5.4.0 – Using Combined Evidence from Replicates to Evaluate ChIP-seq Peaks

MSPC 5.4.0

:: DESCRIPTION

Given a set of peaks from (biological or technical) replicates, MSPC combines the p-values of overlapping enriched regions: users can choose a threshold on the combined significance of overlapping peaks and set a minimum number of replicates where the overlapping peaks should be present. The method allows the “rescue” of weak peaks occuring in more than one replicate and outputs a new set of enriched regions for each replicate.

::DEVELOPER

MSPC team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX

:: DOWNLOAD

 MSPC

:: MORE INFORMATION

Citation

Using combined evidence from replicates to evaluate ChIP-seq peaks.
Jalili V, Matteucci M, Masseroli M, Morelli MJ.
Bioinformatics. 2015 May 7. pii: btv293.

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