Carnac 0.98
:: DESCRIPTION
Carnac is a software tool for analysing the hypothetical secondary structure of a family of homologous RNA. It aims at predicting if the sequences actually share a common secondary structure. When this structure exists, Carnac is then able to correctly recover a large amount of the folded stems. The input is a set of single-stranded RNA sequences that need not to be aligned. The folding strategy relies on a thermodynamic model with energy minimization. It combines information coming from locally conserved elements of the primary structure and mutual information between sequences with covariations too.
::DEVELOPER
Bonsai Bioinformatics – INRIA
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Windows / Linux / MacOsX
- C Complier
:: DOWNLOAD
:: MORE INFORMATION
Citation
CARNAC: folding families of related RNAs
Touzet H. and Perriquet O.
Nucl. Acids Res. (2004) 32 (suppl 2): W142-W145