MosLocator is a tool for researchers who wish to look for insertions in or near one or many genes. It sends queries to a local database; depending on the number of queries and connection speeds, it may take a few seconds or even a couple of minutes for the answer to come back.
CRML (C. elegans Muscle Cis-Regulatory Module Locator) is a web tool for predicting cis-regulatory modules that direct muscle-specific gene expression in C. elegans. CRML makes high quality predictions with a sensitivity of 88% and a positive predictive value of at least 65%. In vivo experimental tests of 12 predicted modules show that 10 of those drive muscle-specific gene expression. These results suggest that CRML is highly accurate in identifying functional sequences important for muscle-specific gene expression and is a valuable tool for guiding experimental designs.
Stormo Lab in Department of Genetics, Washington University
CellExplorer is a package of computer programs to process and analyze 3D confocal image stacks of the model animal C. elegans, and can be applied to several other model systems such as fruit fly embryo/larvae as well. Some other applications include 3D cell/nuclei segmentation, quantification, gene expression analysis, automatic cell naming/annotation, cell targeting, etc.