boostKCP – Boosting k-means Clustering for the Pearson correlation distance

boostKCP

:: DESCRIPTION

boostKCP is a simple but powerful heuristic method for accelerating k-means clustering of large-scale data in life science.

::DEVELOPER

Morishita Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C++

:: DOWNLOAD

boostKCP

:: MORE INFORMATION

Citation

Ichikawa K, Morishita S.
A Simple but Powerful Heuristic Method for Accelerating k-Means Clustering of Large-Scale Data in Life Science.
IEEE/ACM Trans Comput Biol Bioinform. 2014 Jul-Aug;11(4):681-92. doi: 10.1109/TCBB.2014.2306200. PMID: 26356339.

TAGOOS 0.2.1 – Associated Tag SNP Boosting

TAGOOS 0.2.1

:: DESCRIPTION

TAGOOS  (TAG SNP bOOSting) is a nucleotide scoring tool for non-coding (Intronic and intergenic) regions.

::DEVELOPER

The TAGC Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

TAGOOS 

:: MORE INFORMATION

Citation:

González A, Artufel M, Rihet P.
TAGOOS: genome-wide supervised learning of non-coding loci associated to complex phenotypes.
Nucleic Acids Res. 2019 Aug 22;47(14):e79. doi: 10.1093/nar/gkz320. PMID: 31045203; PMCID: PMC6698643.

GWAB – Web Server for Network-based Boosting of Human Genome-wide Association data

GWAB

:: DESCRIPTION

GWAB (genome-wide Association Boosting) is a web server for the network-based boosting of human GWAS data.

::DEVELOPER

Network Biomedicine Laboratory at Yonsei University, Korea

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2017 Jul 3;45(W1):W154-W161. doi: 10.1093/nar/gkx284.
GWAB: a web server for the network-based boosting of human genome-wide association data.
Shim JE, Bang C, Yang S, Lee T, Hwang S, Kim CY, Singh-Blom UM, Marcotte EM, Lee I.

CoreBoost / CoreBoost_HM – Boosting with Stumps for Predicting Transcription Start Sites / using Histone Modification Signal

CoreBoost / CoreBoost_HM

:: DESCRIPTION

CoreBoost is a program for predicting the location of transcription start sites for human polymerase II promoters. It is based on two classifiers, one for CpG related promoters and the other for non-CpG related promoters. Both classifiers apply boosting techniques with stumps and select important small scale as well as large scale sequence features such as position specific core promoter elements and the flexibility of promoter sequences. The current version has more than 30% sensitivity and positive predictive value at 50 bp resolution.

CoreBoost_HMis a program for predicting the location of human polymerase II (Pol II) core-promoters. It is developed based on human Pol II core-promoter predictor CoreBoost by integrating specific histone modification profiles and the DNA sequence features together. Same as Coreboost, CoreBoost_HM is based on two classifiers, one for CpG related promoters and the other for non-CpG related promoters. Both classifiers apply boosting techniques with stumps and select important sequence features and histone modification features. Our analysis suggested that integrating histone modification profiles can provide much higher sensitivity, specificity and high resolution for human core-promoter prediction.

::DEVELOPER

Zhang Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Boosting with stumps for predicting transcription start sites.
Zhao X, Xuan Z, Zhang MQ.
Genome Biol. 2007;8(2):R17.

High-resolution human core-promoter prediction with CoreBoost_HM.
Wang X, Xuan Z, Zhao X, Li Y, Zhang MQ.
Genome Res. 2009 Feb;19(2):266-75. Epub 2008 Nov 7.

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