SEMBA – Single-rEsidue Mutational based Binding Affinity

SEMBA

:: DESCRIPTION

SEMBA is a program for analyzing the binding affinity of amyloid proteins. It uses an energy function that computes the Lennard-Jones, Coulomb, and solvation energies
to determine the effect of a mutation on a protein’s stability.

::DEVELOPER

SEMBA team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

 SEMBA

:: MORE INFORMATION

Citation

Probing the binding affinity of amyloids to reduce toxicity of oligomers in diabetes.
Smaoui MR, Orland H, Waldispühl J.
Bioinformatics. 2015 Mar 15. pii: btv143.

PRODIGY 2.0 – Predicting the Binding Affinity of Protein-protein Complexes

PRODIGY 2.0

:: DESCRIPTION

PRODIGY (PROtein binDIng enerGY prediction) webserver predict of the binding affinity in protein-protein complexes.

::DEVELOPER

BONVIN LAB

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ MacOsX
  • Python

:: DOWNLOAD

 PRODIGY

:: MORE INFORMATION

Citation

PRODIGY: a web server for predicting the binding affinity of protein-protein complexes.
Xue LC, Rodrigues JP, Kastritis PL, Bonvin AM, Vangone A.
Bioinformatics. 2016 Aug 8. pii: btw514.