Tag: ATHENA

ATHENA 1.1.0 – Discover Epistasis among Quantitative Trait Loci

ATHENA 1.1.0

:: DESCRIPTION

ATHENA (the Analysis Tool for Heritable and Environmental Network Associations) results in clear performance improvements for discovering gene-gene interactions that influence human traits. We employed an alternative tree-based crossover, backpropagation for locally fitting neural network weights, and incorporation of domain knowledge obtainable from publicly accessible biological databases for initializing the search for gene-gene interactions. We tested these modifications in silico using simulated datasets.

::DEVELOPER

Ritchie Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 ATHENA

:: MORE INFORMATION

Citation:

ATHENA: A knowledge-based hybrid backpropagation-grammatical evolution neural network algorithm for discovering epistasis among quantitative trait Loci.
Turner SD, Dudek SM, Ritchie MD.
BioData Min. 2010 Sep 27;3(1):5.

Athena r4 – Modular CAD/CAM software for Synthetic Biology

Athena r4

:: DESCRIPTION

Athena is a software that allows biological models to be constructed as modules. Modules can be connected to one another without altering the modules themselves. In addition, Athena houses various tools useful for designing synthetic networks including tools to perform simulations, automatically derive transcription rate expressions, and view and edit synthetic DNA sequences. New tools can be incorporated into Athena without modifying existing program via a plugin interface, IronPython scripts, Systems Biology Workbench interfacing and the R statistical language.

::DEVELOPER

Frank T. Bergmann (fbergman@u.washington.edu)

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

 Athena

:: MORE INFORMATION

Citation

Athena: Modular CAM/CAD Software for Synthetic Biology
Deepak Chandran, Frank T. Bergmann, Herbert M. Sauro