CSM-lig / mCSM-lig – A Web Server for Assessing and Comparing Protein-small molecule Affinities

CSM-lig / mCSM-lig

:: DESCRIPTION

CSM-lig is a web server tailored to predict the binding affinity of a protein-small molecule complex based on structural signatures.

mCSM-lig is a structure-guided in silico approach for directly quantifying the effects of single-point missense mutations on affinities of small molecules for proteins.

::DEVELOPER

Biosig Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

Pires DE, Blundell TL, Ascher DB.
mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance.
Sci Rep. 2016 Jul 7;6:29575. doi: 10.1038/srep29575. PMID: 27384129; PMCID: PMC4935856.

CSM-lig: a web server for assessing and comparing protein-small molecule affinities.
Pires DE, Ascher DB.
Nucleic Acids Res. 2016 May 5. pii: gkw390.

SDBP 1.0 – Assessing Statistical Reliability of Phylogenetic Trees

SDBP 1.0

:: DESCRIPTION

SDBP (speedy double bootstrap probability) is R package for assenssing the statistical reliability of phylogenetic trees.

::DEVELOPER

Akiyama Laboratory, Tokyo Institute of Technology

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux / Windows/ MacOsX
R package

:: DOWNLOAD

SDBP

:: MORE INFORMATION

Citation

Ren, A., Ishida, T. and Akiyama, Y., 2013.
Assessing statistical reliability of phylogenetic trees via a speedy double bootstrap method
Molecular Phylogenetic of evolutionm, 67(2), 429-435. doi:10.1016/j.ympev.2013.02.011