ALLOY 0.2 – Ancestry Inference on Local Genomic Segments

ALLOY 0.2

:: DESCRIPTION

ALLOY (Accurate Local Ancestry Inference) is a fast and accurate method for local ancestry inference, which is the problem of labeling each position of the genome with an ancestral origin.

::DEVELOPER

Serafim’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/MacOsX
  • Java

:: DOWNLOAD

 ALLOY

:: MORE INFORMATION

Citation

J Comput Biol. 2013 Mar;20(3):199-211. doi: 10.1089/cmb.2012.0088.
Ancestry inference in complex admixtures via variable-length Markov chain linkage models.
Rodriguez JM, Bercovici S, Elmore M, Batzoglou S.

RFMix 1.5.4 – A Discriminative method for Local Ancestry Inference

RFMix 1.5.4

:: DESCRIPTION

RFMix is a powerful discriminative modeling approach that is faster (~30×) and more accurate than existing methods.RFMix is capable of learning from the admixed samples themselves to boost performance and autocorrect phasing errors. RFMix shows high sensitivity and specificity in simulated Hispanics/Latinos and African Americans and admixed Europeans, Africans, and Asians.

:: DEVELOPER

the Bustamante Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • R package

:: DOWNLOAD

 RFMix

:: MORE INFORMATION

Citation

Am J Hum Genet. 2013 Aug 8;93(2):278-88. doi: 10.1016/j.ajhg.2013.06.020. Epub 2013 Aug 1.
RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference.
Maples BK1, Gravel S, Kenny EE, Bustamante CD.