MitoScape v1.0 – Machine-learning workflow for Aligning mtDNA from NGS data

MitoScape v1.0

:: DESCRIPTION

MitoScape is a novel, big-data, software for extracting mitochondrial DNA sequences from NGS.

::DEVELOPER

Larry N. Singh

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

MitoScape

:: MORE INFORMATION

Citation

Singh LN, Ennis B, Loneragan B, Tsao NL, Lopez Sanchez MIG, Li J, Acheampong P, Tran O, Trounce IA, Zhu Y, Potluri P; Regeneron Genetics Center, Emanuel BS, Rader DJ, Arany Z, Damrauer SM, Resnick AC, Anderson SA, Wallace DC.
MitoScape: A big-data, machine-learning platform for obtaining mitochondrial DNA from next-generation sequencing data.
PLoS Comput Biol. 2021 Nov 11;17(11):e1009594. doi: 10.1371/journal.pcbi.1009594. Epub ahead of print. PMID: 34762648.

Sprites 0.3.0 – Deletion Finder through re-aligning the Whole Soft-clipping Read

Sprites 0.3.0

:: DESCRIPTION

Sprites is a sv caller that specializes in detecting deletion from low-coverage sequencing data. It works by identifying split reads from alignments based on soft-clipping information.

::DEVELOPER

Zhen Zhang (zhangz@csu.edu.cn)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • MacOsX/Linux

:: DOWNLOAD

 Sprites

:: MORE INFORMATION

Citation

Sprites: detection of deletions from sequencing data by re-aligning split reads.
Zhang Z, Wang J, Luo J, Ding X, Zhong J, Wang J, Wu FX, Pan Y.
Bioinformatics. 2016 Feb 1. pii: btw053.

PocketAlign – Aligning Binding Sites in Protein Structures

PocketAlign

:: DESCRIPTION

PocketAlign is a web server of comparison of binding sites helps identify functional similarities and also identify drug cross-reactivities

::DEVELOPER

Chandra lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No

:: MORE INFORMATION

Citation

J Chem Inf Model. 2011 Jul 25;51(7):1725-36. doi: 10.1021/ci200132z. Epub 2011 Jun 21.
PocketAlign a novel algorithm for aligning binding sites in protein structures.
Yeturu K, Chandra N.

Opal v3.0 – Aligning multiple Biological Sequences

Opal v3.0

:: DESCRIPTION

Opal is software for aligning multiple biological sequences.

::DEVELOPER

Opal team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOs

:: DOWNLOAD

Opal

:: MORE INFORMATION

Citation

Multiple alignment by aligning alignments.
Wheeler TJ, Kececioglu JD.
Bioinformatics. 2007 Jul 1;23(13):i559-68.

DAFS 0.0.3 – Simultaneous Aligning and Folding of RNA Sequences by Dual Decomposition

DAFS 0.0.3

:: DESCRIPTION

DAFS is a novel algorithm that simultaneously aligns and folds RNA sequences based on maximizing expected accuracy of a predicted common secondary structure and its alignment.

::DEVELOPER

Computational Biology Research Center (CBRC),

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 DAFS

:: MORE INFORMATION

Citation:

DAFS: simultaneous aligning and folding of RNA sequences via dual decomposition.
Sato K, Kato Y, Akutsu T, Asai K, Sakakibara Y.
Bioinformatics. 2012 Dec 15;28(24):3218-24. doi: 10.1093/bioinformatics/bts612.

GR-Align 1.5 – Aligning Protein Structures

GR-Align 1.5

:: DESCRIPTION

GR-Align (GRaphlet-based Aligner) is a fast heuristic procedure for aligning/comparing protein structures according to the Contact Map Opverlap maximization (CMO) paradigm. The algorithm is based on a Needleman-Wunch algorithm where the cost for matching two residues is their graphlet degree similarity.

GR-Align packages contains three software: CMap, DCount, and GR-Align:
CMap converts protein structures (.pdb) files into contact map graphs (leda graphs .gw)
DCount computes the graphlet degree signatures (.ndump files) from Contact Maps
GR-Align aligns protein structures (requieres both contact maps and signatures files)

::DEVELOPER

Nataša Pržulj

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 GR-Align

:: MORE INFORMATION

Citation:

Bioinformatics. 2014 May 1;30(9):1259-65. doi: 10.1093/bioinformatics/btu020. Epub 2014 Jan 17.
GR-Align: fast and flexible alignment of protein 3D structures using graphlet degree similarity.
Malod-Dognin N1, Pržulj N.

Graemlin 2.01 – Aligning Multiple Global Protein Interaction Networks

Graemlin 2.01

:: DESCRIPTION

Graemlin is a tool for aligning multiple global protein interaction networks; Graemlin also supports search for homology between a query module of proteins and a database of interaction networks.

::DEVELOPER

Serafim Batzoglou

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 Graemlin

:: MORE INFORMATION

Citation

Graemlin: general and robust alignment of multiple large interaction networks.
Flannick J, Novak A, Srinivasan BS, McAdams HH, Batzoglou S.
Genome Res. 2006 Sep;16(9):1169-81