Tag: AGE

MutationTaster 2021 – Mutation Prediction for the Deep-sequencing Age

MutationTaster 2021

:: DESCRIPTION

MutationTaster is a free web-based application to evaluate DNA sequence variants for their disease-causing potential. The software performs a battery of in silico tests to estimate the impact of the variant on the gene product / protein.

::DEVELOPER

MutationTaster team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser
:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Steinhaus R, Proft S, Schuelke M, Cooper DN, Schwarz JM, Seelow D.
MutationTaster2021.
Nucleic Acids Res. 2021 Jul 2;49(W1):W446-W451. doi: 10.1093/nar/gkab266. PMID: 33893808; PMCID: PMC8262698.

Schwarz JM, Cooper DN, Schuelke M, Seelow D.
MutationTaster2: mutation prediction for the deep-sequencing age.
Nat Methods. 2014 Apr;11(4):361-2. doi: 10.1038/nmeth.2890. PMID: 24681721.

miRNACon – Influence of Confounding Factors Age and Sex on microRNA

miRNACon

:: DESCRIPTION

miRNACon is a web-based application to test individual miRNAs or miRNA signatures for their likelihood of being influenced.

::DEVELOPER

Chair for clinical bioinformatics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

Clin Chem. 2014 Sep;60(9):1200-8. doi: 10.1373/clinchem.2014.224238. Epub 2014 Jun 30.
Influence of the confounding factors age and sex on microRNA profiles from peripheral blood.
Meder B1, Backes C, Haas J, Leidinger P, Stähler C, Großmann T, Vogel B, Frese K, Giannitsis E, Katus HA, Meese E, Keller A.

AGE 0.4 – Optimal Alignment of Sequences with SVs

AGE 0.4

:: DESCRIPTION

AGE (Alignment with Gap Excision) is a tools that implements an algorithm for optimal alignment of sequences with SVs.

::DEVELOPER

Gerstein Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 AGE

:: MORE INFORMATION

Citation:

Bioinformatics. 2011 Mar 1;27(5):595-603. Epub 2011 Jan 13.
AGE: defining breakpoints of genomic structural variants at single-nucleotide resolution, through optimal alignments with gap excision.
Abyzov A, Gerstein M.