T2DAG – Hotelling’s T 2-type Test for detecting differentially Expressed Gene Pathways

T2DAG

:: DESCRIPTION

T2-DAG is an R package of DAG-informed two-sample test for mean difference in the vector of gene expression levels of a pathway. In addition to gene expression data, the method efficiently leverages axiliary pathway information on gene interactions through a linear structural equation model.

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::DEVELOPER

Jin Jin

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux
  • R

:: DOWNLOAD

T2-DAG

:: MORE INFORMATION

Citation:

Jin J, Wang Y.
T2-DAG: a powerful test for differentially expressed gene pathways via graph-informed structural equation modeling.
Bioinformatics. 2021 Nov 10:btab770. doi: 10.1093/bioinformatics/btab770. Epub ahead of print. PMID: 34755844.

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