T-ACE (ranscriptome Analysis and Comparison Explorer) was developed for the analysis and organization of transcriptome projects but is also helpful for the organization of small sequence datasets e.g. extracts of a large transcriptome databases. T-ACE does not provide an assembly function, thus data gained by NGS projects (e.g. 454, Illumina, SoliD) have to be assembled prior to the upload (e.g. using Newbler, Celera or TGICL). For transcriptome comparisons T-ACE was designed to work with a dataset composed of several transcriptomes of different treatments or tissues, which are assembled into a consensus transcriptome.
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The Transcriptome Analysis and Comparison Explorer – T-ACE: a platform-independent, graphical tool to process large RNAseq data sets of non-model organisms.
E.E.R. Philipp; L. Kraemer; D. Mountfort; M. Schilhabel; S. Schreiber; P. Rosenstiel
Bioinformatics 2012; doi: 10.1093/bioinformatics/bts056