SPELL is a query-driven search engine for large gene expression microarray compendia. Given a small set of query genes, SPELL identifies which datasets are most informative for these genes, then within those datasets additional genes are identified with expression profiles most similar to the query set.
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Bioinformatics. 2007 Oct 15;23(20):2692-9.
Exploring the functional landscape of gene expression: directed search of large microarray compendia.
Hibbs MA, Hess DC, Myers CL, Huttenhower C, Li K, Troyanskaya OG.