SORA offers an effective and reliable way to compare gene function based on Semantic Overlap Ration Annotation.
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Bioinformatics. 2013 Jun 1;29(11):1424-32. doi: 10.1093/bioinformatics/btt160. Epub 2013 Apr 9.
Measuring gene functional similarity based on group-wise comparison of GO terms.
Teng Z1, Guo M, Liu X, Dai Q, Wang C, Xuan P.