SOCKET 3.03 / iSocket 0.3.1 – Identifies Knobs-into-holes packing in Protein Structures

SOCKET 3.03 / iSocket 0.3.1

:: DESCRIPTION

The SOCKET program finds the Knobs-into-Holes mode of packing between alpha-helices which is characteristic of coiled coils. It unambiguously defines the beginning and end of coiled-coil motifs in protein structures and assigns a heptad register to the sequence, highlighting the core-residues with a RasMol script if required.

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iSocket is a set of computational tools written in Python as an add-on to the ISAMBARD software suite.

::DEVELOPER

WOOLFSON lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler / Python

:: DOWNLOAD

 SOCKET / iSocket

:: MORE INFORMATION

Citation

Heal JW, Bartlett GJ, Wood CW, Thomson AR, Woolfson DN.
Applying graph theory to protein structures: an Atlas of coiled coils.
Bioinformatics. 2018 Oct 1;34(19):3316-3323. doi: 10.1093/bioinformatics/bty347. PMID: 29722888; PMCID: PMC6157074.

Walshaw, J. & Woolfson, D.N. (2001)
Socket: a program for identifying and analysing coiled-coil motifs within protein structures.
J. Mol. Biol., 307 (5), 1427-1450