Sleipnir 3.0 / COALESCE – Library for Computational Functional Genomics

Sleipnir 3.0 / COALESCE

:: DESCRIPTION

Sleipnir is a C++ library enabling efficient analysis, integration, mining, and machine learning over genomic data. This includes a particular focus on microarrays, since they make up the bulk of available data for many organisms, but Sleipnir can also integrate a wide variety of other data types, from pairwise physical interactions to sequence similarity or shared transcription factor binding sites.

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COALESCE (Combinatorial Algorithm for Expression and Sequence-based Cluster Extraction) can use large collections of genomic data and Bayesian integration to predict coregulated gene modules, the conditions of regulation, and the consensus binding motifs for regulation.

::DEVELOPER

Troyanskaya Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux
  • C Compiler

:: DOWNLOAD

 Sleipnir

:: MORE INFORMATION

Citation

Curtis Huttenhower, Mark Schroeder, Maria D. Chikina, and Olga G. Troyanskaya
The Sleipnir library for computational functional genomics”,
Bioinformatics. 2008 Jul 1;24(13):1559-61. Epub 2008 May 21.

Bioinformatics. 2009 Dec 15;25(24):3267-74. doi: 10.1093/bioinformatics/btp588.
Detailing regulatory networks through large scale data integration.
Huttenhower C, Mutungu KT, Indik N, Yang W, Schroeder M, Forman JJ, Troyanskaya OG, Coller HA.

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