SIfTER 2015 – Mapping Protein Conformation Spaces

SIfTER 2015

:: DESCRIPTION

SIfTER is a structure-guided memetic, cellular, and multiscale evolutionary algorithm for mapping protein conformation spaces. It is based instead on stochastic optimization to circumvent the computational challenge of exploring the breadth of a protein’s structure space.

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::DEVELOPER

Computational Biology lab, George Mason University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

SIfTER

:: MORE INFORMATION

Citation

Clausen R, Ma B, Nussinov R, Shehu A.
Mapping the Conformation Space of Wildtype and Mutant H-Ras with a Memetic, Cellular, and Multiscale Evolutionary Algorithm.
PLoS Comput Biol. 2015 Sep 1;11(9):e1004470. doi: 10.1371/journal.pcbi.1004470. PMID: 26325505; PMCID: PMC4556523.

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