ShatterSeek v0.5 – Identification of Chromothripsis Events from Whole-genome Sequencing data

ShatterSeek v0.5

:: DESCRIPTION

ShatterSeek is an R package that provides utilities to detect chromothripsis events from next-generation sequencing (NGS) data. It takes as input copy number (CN) and structural variation (SV) calls calculated with the user preferred method. Hence, it is compatible with virtually any CN and SV caller.

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::DEVELOPER

Peter Park’s lab at CBMI, Harvard Medical School

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX
  • R

:: DOWNLOAD

ShatterSeek

:: MORE INFORMATION

Citation

Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS; PCAWG Structural Variation Working Group, Park PJ; PCAWG Consortium.
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.
Nat Genet. 2020 Mar;52(3):331-341. doi: 10.1038/s41588-019-0576-7. Epub 2020 Feb 5. Erratum in: Nat Genet. 2020 May 13;: PMID: 32025003; PMCID: PMC7058534.

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