SAAFEC-SEQ – Pedict the stability Changes upon a Single Mutation in Protein

SAAFEC-SEQ

:: DESCRIPTION

SAAFEC-SEQ is an online application for calculating folding free energy changes in proteins caused by missense mutations for provided protein sequence.

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::DEVELOPER

Professor Emil Alexov Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

SAAFEC-SEQ

:: MORE INFORMATION

Citation

Li G, Panday SK, Alexov E.
SAAFEC-SEQ: A Sequence-Based Method for Predicting the Effect of Single Point Mutations on Protein Thermodynamic Stability.
Int J Mol Sci. 2021 Jan 9;22(2):606. doi: 10.3390/ijms22020606. PMID: 33435356; PMCID: PMC7827184.

SAAFEC: Predicting the Effect of Single Point Mutations on Protein Folding Free Energy Using a Knowledge-Modified MM/PBSA Approach.
Getov I, Petukh M, Alexov E.
Int J Mol Sci. 2016 Apr 7;17(4). pii: E512. doi: 10.3390/ijms17040512.