RVS 20140305 – Genetic Association with NGS data

RVS 20140305

:: DESCRIPTION

The RVS (robust variance score) is a novel likelihood-based method for genetic association with NGS data from external control groups. RVS substitutes genotype calls by their expected values given observed sequence data and implements a robust variance estimate for the score statistic.

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::DEVELOPER

Strug lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R

:: DOWNLOAD

 RVS

:: MORE INFORMATION

Citation

Association analysis using next-generation sequence data from publicly available control groups: the robust variance score statistic.
Derkach A, Chiang T, Gong J, Addis L, Dobbins S, Tomlinson I, Houlston R, Pal DK, Strug LJ.
Bioinformatics. 2014 Apr 14. pii: btu196.