RVD – Rare Single Nucleotide Variant Detection using Next-generation Sequencing

RVD

:: DESCRIPTION

RVD is a standalone algorithm for ultrasensitive rare single nucleotide variant detection using next-generation sequencing. The RVD program takes BAM files of deep sequencing reads in as input. Using a Beta-Binomial model, the algorithm estimates the error rate at each base position in the reference sequence.

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::DEVELOPER

Ji Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  •  MacOsX / Linux
  • MatLab
  • Samtools

:: DOWNLOAD

  RVD

:: MORE INFORMATION

Citation

RVD: a command-line program for ultrasensitive rare single nucleotide variant detection using targeted next-generation DNA resequencing.
Cushing A, Flaherty P, Hopmans E, Bell JM, Ji HP.
BMC Res Notes. 2013 May 23;6:206.