PurityEst – Estimating Purity of Human Tumor Samples using Next-generation Sequencing Data

PurityEst

:: DESCRIPTION

PurityEst is a novel algorithm which infers the tumor purity level from the allelic differential representation of heterozygous loci with somatic mutations in a human tumor sample with a matched normal tissue using next-generation sequencing data.

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::DEVELOPER

Xiaoping Su

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

 PurityEst

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Sep 1;28(17):2265-6. doi: 10.1093/bioinformatics/bts365.
PurityEst: estimating purity of human tumor samples using next-generation sequencing data.
Su X, Zhang L, Zhang J, Meric-Bernstam F, Weinstein JN.