PPI / PPI_RF – Prediction of Protein-Protein Interactions

PPI / PPI_RF

:: DESCRIPTION

The web-server PPI  is used to predict the protein-protein interaction.The protein sequence are represented by chaos game representation and wavelets transform. The chaos game representation encodes the amino acid position of the proteion and then two discrete series are gotten. The wavelets transform is used to analyse the two series. Finally the random forests algorithm is used for PPIs prediction.

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The web-server PPI_RF is used to predict the protein-protein interaction. Based on the physicochemical descriptors, a protein could be converted into several digital signals and then wavelet transform was used to analyze them. With such a formulation frame to represent the samples of protein sequences, the random forests algorithm was adopted to conduct prediction.

::DEVELOPER

Xiao Lab

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Prediction of protein-protein interactions using chaos game representation and wavelet transform via the random forest algorithm.
Jia JH, Liu Z, Chen X, Xiao X, Liu BX.
Genet Mol Res. 2015 Oct 2;14(4):11791-805. doi: 10.4238/2015.

Prediction of Protein-Protein Interactions with Physicochemical Descriptors and Wavelet Transform via Random Forests.
Jia J, Xiao X, Liu B.
J Lab Autom. 2015 Apr 16. pii: 2211068215581487