PolyaPeak 0.4 – ChIP-seq Peak Reranking tool using mixture of Multivariate Polya Ditributions

PolyaPeak 0.4

:: DESCRIPTION

PolyaPeak is an R package for ranking ChIP-seq peaks with shape information. polyaPeak uses a Bayesian hierarchical model to incorporate the peak shapes in the ranking. The shapes are described by a mixture of multivariate Polya distributions. Real data analyses show that polyaPeak outperforms several popular peak calling software including MACS, CisGenome and PICS.

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::DEVELOPER

Hao Wu, Ph.D.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows /Linux/ MacOsX
  • R

:: DOWNLOAD

 PolyaPeak

:: MORE INFORMATION

Citation

PLoS One. 2014 Mar 7;9(3):e89694. doi: 10.1371/journal.pone.0089694. eCollection 2014.
PolyaPeak: detecting transcription factor binding sites from ChIP-seq using peak shape information.
Wu H1, Ji H