Parepro (Prediction of amino acid replacement probability) is a methodof identifying which non-synonymous single base changes have a deleterious effect on protein function, based on support vector machine (SVM).
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences
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BMC Bioinformatics. 2007 Nov 16;8:450.
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines.
Tian J1, Wu N, Guo X, Guo J, Zhang J, Fan Y.