NQ-Flipper 2.7 – Validate Asparagine and Glutamine Side-chain Amide Rotamers in Protein Structures

NQ-Flipper 2.7

:: DESCRIPTION

NQ-Flipper recognizes unfavorable rotamers of Asn and Gln residues in protein structures. This service is applicable to structures obtained from X-ray crystallography, NMR or modeling studies. The method is based on knowledge-based potentials of mean force compiled from a database of known protein structures determined by X-ray crystallography. The potentials are then refined by several cycles of rotamer correction and recompilation of potentials. The refined potentials are used here to validate or correct asparagine and glutamine amide rotamers.

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::DEVELOPER

C.A.M.E. – the Center of Applied Molecular Engineering.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

  NQ-Flipper

:: MORE INFORMATION

Citation

Weichenberger, C. X., and Sippl, M. J. (2006)
NQ-Flipper: Validation and Correction of Asparagine/Glutamine Amide Rotamers in Protein Crystal Structures.
Bioinformatics, 22, 1397-1398.

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