MuSE 1.0-RC – Somatic Point Mutation Caller

MuSE 1.0-RC

:: DESCRIPTION

MuSE (Mutation calling using a Markov Substitution model for Evolution) is a novel approach for modeling the evolution of the allelic composition of the tumor and normal tissue at each reference base.

Advertisement

::DEVELOPER

Statistical Bioinformatics Lab, The University of Texas M. D. Anderson Cancer Center

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /MacOsX/Windows
  • C++ Compiler

:: DOWNLOAD

MuSE

:: MORE INFORMATION

Citation

Fan Y, Xi L, Hughes DS, Zhang J, Zhang J, Futreal PA, Wheeler DA, Wang W.
MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data.
Genome Biol. 2016 Aug 24;17(1):178. doi: 10.1186/s13059-016-1029-6. PMID: 27557938; PMCID: PMC4995747.

Leave a Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.