MuSE 1.0-RC
:: DESCRIPTION
MuSE (Mutation calling using a Markov Substitution model for Evolution) is a novel approach for modeling the evolution of the allelic composition of the tumor and normal tissue at each reference base.
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::DEVELOPER
Statistical Bioinformatics Lab, The University of Texas M. D. Anderson Cancer Center
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux /MacOsX/Windows
- C++ Compiler
:: DOWNLOAD
:: MORE INFORMATION
Citation
Fan Y, Xi L, Hughes DS, Zhang J, Zhang J, Futreal PA, Wheeler DA, Wang W.
MuSE: accounting for tumor heterogeneity using a sample-specific error model improves sensitivity and specificity in mutation calling from sequencing data.
Genome Biol. 2016 Aug 24;17(1):178. doi: 10.1186/s13059-016-1029-6. PMID: 27557938; PMCID: PMC4995747.