miReduce

:: DESCRIPTION

miReduce correlates the logarithm of expression fold changes of a set of genes with the motif content of the regulatory sequences of these genes. In particular, it correlates the genome wide mRNA log fold changes in experiments involving the knockout/knockdown/overexpression of one or more miRNAs with the motif content of the 3’UTRs. The model is based on linear regression, and is intended for genome-wide studies.

::DEVELOPER

N. Rajewsky Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux
• Perl

:: DOWNLOAD

 miReduce

:: MORE INFORMATION

Citation

Pranidhi Sood, Azra Krek, Mihaela Zavolan, Giuseppe Macino, and Nikolaus Rajewsky
“Cell-type-specific signatures of microRNAs on target mRNA expression“,
Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2746-51. Epub 2006 Feb 13.