MIRA – Methylation-based Inference of Regulatory Activity

MIRA

:: DESCRIPTION

The MIRA package aggregates DNA methylation across the genome for instances of a genomic feature like histone ChIP peaks, transcription factor ChIP peaks, or open chromatin regions in order to give a single signature and score for that feature, which may be used to infer regulatory activity.

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::DEVELOPER

Sheffield lab of computational biology

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • R

:: DOWNLOAD

MIRA

:: MORE INFORMATION

Citation

Lawson JT, Tomazou EM, Bock C, Sheffield NC.
MIRA: an R package for DNA methylation-based inference of regulatory activity.
Bioinformatics. 2018 Aug 1;34(15):2649-2650. doi: 10.1093/bioinformatics/bty083. PMID: 29506020; PMCID: PMC6061852.

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