LiRA

:: DESCRIPTION

LiRA is a computational tool for removing amplification artifacts from single-cell DNA sequencing data and estimating mutation rates in single cells.

::DEVELOPER

Peter Park’s lab at CBMI, Harvard Medical School

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux / MacOsX
• R
• Python

:: DOWNLOAD

LiRA

:: MORE INFORMATION

Citation

Bohrson CL, Barton AR, Lodato MA, Rodin RE, Luquette LJ, Viswanadham VV, Gulhan DC, Cortés-Ciriano I, Sherman MA, Kwon M, Coulter ME, Galor A, Walsh CA, Park PJ.
Linked-read analysis identifies mutations in single-cell DNA-sequencing data.
Nat Genet. 2019 Apr;51(4):749-754. doi: 10.1038/s41588-019-0366-2. Epub 2019 Mar 18. PMID: 30886424; PMCID: PMC6900933.