LINDEL
:: DESCRIPTION
LINDEL is the Integrated Design system for LincRNA deletion (LINDEL) , which was implemented on an interactive web genome-browser. LINDEL system makes possible the design of sgRNAs that i) are based on improved annotations of human and mouse lincRNA genes, ii) function as pairs for the deletion of both whole and segmental regions of these genes, again based on comprehensive functional annotations, and iii) efficiently generate mutations because of both sequence- and secondary structure-based features.
:: DEVELOPER
BIG Lab. (BIOINFORMATICS & GENOMICS)
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Web browser
:: DOWNLOAD
:: MORE INFORMATION
Citation:
Lee HJ, Gopalappa R, Sunwoo H, Choi SW, Ramakrishna S, Lee JT, Kim HH, Nam JW.
En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements.
Nucleic Acids Res. 2019 May 7;47(8):3875-3887. doi: 10.1093/nar/gkz109. PMID: 30783652; PMCID: PMC6486550.