HiSIF 1.0

:: DESCRIPTION

HiSIF is a novel computational software tool on Hi-C data analysis, including a Poisson Mixture Model, with an Expectation Maximization algorithm (EM) followed by a power-law decay background model to filter background-ligation events.

::DEVELOPER

Jin Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux

:: DOWNLOAD

HiSIF

:: MORE INFORMATION

Citation

Zhou Y, Cheng X, Yang Y, Li T, Li J, Huang TH, Wang J, Lin S, Jin VX.
Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops.
Genome Med. 2020 Aug 12;12(1):69. doi: 10.1186/s13073-020-00769-8. PMID: 32787954; PMCID: PMC7425017.