GUIDANCE 2.02

:: DESCRIPTION

The GUIDANCE web-server is a powerful and user-friendly tool for assigning a confidence score for each residue, column, and sequence in an alignment and for projecting these scores onto the MSA. The server points to columns and sequences that are unreliably aligned and enables their automatic removal from the MSA, in preparation for downstream analyses.

::DEVELOPER

GUIDANCE Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

• Linux
• MAFFT
• PRANK
• CLUSTALW
• Perl
• BioPerl
• Ruby

:: DOWNLOAD

  GUIDANCE

:: MORE INFORMATION

Citation

GUIDANCE2: accurate detection of unreliable alignment regions accounting for the uncertainty of multiple parameters.
Sela I, Ashkenazy H, Katoh K, Pupko T.
Nucleic Acids Res. 2015 Apr 16. pii: gkv318.

Penn, O., Privman, E., Ashkenazy, H., Landan, G., Graur, D. and Pupko, T. (2010).
GUIDANCE: a web server for assessing alignment confidence scores.
Nucleic Acids Research, 2010 Jul 1; 38 (Web Server issue):W23-W28; doi: 10.1093/nar/gkq443