GRAMMy – Shotgun Metagenomics Analysis

GRAMMy

:: DESCRIPTION

GRAMMy is a computational framework developed for Genome Relative Abundance using Mixture Model theory (GRAMMy) based estimation. Accurate estimation of microbial community composition based on metagenomic sequencing data is fundamental for metagenomics analysis. Prevalent estimation methods are mainly based on directly summarizing alignment results or its variants; often result in biased and/or unstable estimates.

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::DEVELOPER

Ji Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX
  • Python

:: DOWNLOAD

 GRAMMy

:: MORE INFORMATION

Citation

PLoS One. 2011;6(12):e27992. doi: 10.1371/journal.pone.0027992. Epub 2011 Dec 6.
Accurate genome relative abundance estimation based on shotgun metagenomic reads.
Xia LC1, Cram JA, Chen T, Fuhrman JA, Sun F.